Open access
Jul 2026
Enrichment-free deep proteomics enables proteome-scale analysis of methionine oxidation
Abstract Advances in mass spectrometry (MS)-based proteomics have enabled the large-scale characterization of posttranslational modifications (PTMs) through affinity-based enrichment. However, this technique introduces a bias towards selectively enrichable modifications, thus leaving oxidative modifications underexplor...
Hiromasa Mitsui, Yusei Okuda, R. Konno et al.
· DNA Research · 0 citations