Author

D. Newman

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Open access Sep 2026

Genome-wide fitness profiling reveals flagellar rotation as an energetic liability during anaerobic maintenance in Pseudomonas aeruginosa

The results show that in a low-powered maintenance state, limiting energy-dissipating processes, such as proton-motive force loss through flagellar rotation, supports cell survival, and suggest that growth-arrested cells live at a bioenergetic knife’s edge, where an energy-dissipating process can tip the balance betwee...

Kemal Demirer, R. A. Melnyk, Hans K. Carlson et al. · bioRxiv · 0 citations

Open access Sep 2026

Dynamic and distinct physiological responses by a soil bacterium promote survival along a desiccation continuum

Results indicate that diverse cellular properties contribute to soil bacterial desiccation tolerance, whose relative response and fitness are tuned to different challenges imposed by soil drying dynamics.

Jarek V. Kwiecinski, Georgia R. Squyres, Dani Or et al. · mBio · 0 citations

Open access Jul 2026

Discovery of a phenazine–thiol conjugase from sparse data using genome-informed machine learning

It is shown that integrating genome-informed data augmentation with contrastive learning in protein language space enables identification of phenazine-interacting proteins starting from only 14 known phenazine modifying sequences, and coupling comparative genomics with protein machine learning can convert “small data”...

Xiaoyu Shan, I. Trindade, N. Glasser et al. · Proceedings of the National... · 0 citations