Open access
Sep 2026
Experimental Framework to Investigate Glioma in Organotypic Human Cortex
Background Gliomas are primary brain tumors that integrate into the surrounding brain via neuron-glioma synapses and disrupt normal neuronal functioning. Recent work links tumor-brain connectivity to clinical measures such as patients’ functional status. However, few experimental systems allow the visualization of tumo...
Lotte R. Woltheus, L. Baudouin, M. van Lingen et al.
· bioRxiv · 0 citations