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Open access Sep 2026

Three Cases of Merkel Cell Carcinoma Treated With Lutetium-177 Oxodotreotide.

Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine skin cancer associated with early metastasis and poor outcomes in the advanced stages. Immune checkpoint inhibitors (ICIs), particularly avelumab, represent the first-line therapy for metastatic MCC. However, effective treatment options after progression...

Michitoshi Kurisaki, E. Nakano, Y. Sakai et al. · 0 citations
Open access Oct 2026

Melanoma Recurrence Prediction Using a Tissue-Free Epigenomic Molecular Residual Disease Assay: a Multicenter Prospective Observational Study (COSMOS-MEL01).

Despite recent adoption of perioperative therapy for high-risk melanoma, its overall survival benefit remains unclear, highlighting the need for biomarkers to identify patients likely to benefit from treatment. Detection of circulating tumor DNA (ctDNA) after definitive treatment predicts recurrence, and emerging molec...

Yoshiaki Nakamura, K. Namikawa, D. Ogata et al. · 0 citations

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