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Author

D. Pincus

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Open access Aug 2026

A Statistical Approach to Cellular Resource Allocation Models

Understanding how cells regulate growth despite molecular complexity remains a central question in quantitative biology. While thousands of genes respond to environmental perturbations, the population growth rate varies smoothly across conditions, suggesting the existence of simple organizing principles. Here, we show...

Ankita Roychoudhury, D. Pincus, Madhav Mani · 0 citations
Open access Aug 2026

Emergent 3D genome reorganization and graded gene control from the stepwise assembly of transcriptional condensates.

Transcriptional condensates are clusters of transcription factors, coactivators, and RNA Pol II associated with gene activation, yet how they assemble and function within the cell remains unclear. Here, we show that transcriptional condensates form in a stepwise manner to enable both graded and three-dimensional (3D) g...

Surabhi Chowdhary, S. Paracha, Lucas Dyer et al. · 1 citation

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