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Open access 2026

Synthesis, characterization, biological evolution and docking study of Resorcin[4]arene hybrid thymine acetic acid derivatives

Resorcin[4]arenes are an important class of supramolecular macrocycles possessing remarkable host-guest recognition properties and broad pharmacological potential. In the present study, a novel series of resorcin[4]arene-thymine acetic acid hybrid derivatives (6a–k) was synthesized through an efficient coupling strateg...

J. Gajjar, Rajesh H. Vekariya, Manoj A. Vora et al. · 0 citations
Open access Sep 2026

Design and Synthesis of Novel 1,2,3‐Triazole Conjugates Featuring Hydroxamic Acid and Sulfonamide Moieties: Exploring Dual Pharmacophores for Enhanced Biological Activity

A new series of N‐hydroxy‐1‐(4‐(aryl sulfonamido)phenyl)‐1H‐1,2,3‐triazole‐4‐carboxamide derivatives (8a‐j) were synthesized through a concise multistep route integrating three key pharmacophores: the 1,2,3‐triazole core, an aryl sulfonamide moiety, and an N‐hydroxycarboxamide group. Biological evaluation demonstrated...

Dinesh Pagar, Ranjay Shaw, Hemant Suryavanshi et al. · 0 citations

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