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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

D. Redmond

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1 paper indexed here

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Open access Aug 2026

JNK and p53 cause human and mouse β cell death during excessive unfolded protein response

In human β cells, pharmacological inhibition of both JNK and p53 improved β cell survival during GRP78 knockdown–induced UPR, and possible therapeutic targets to preserve insulin secretory capacity in diabetes are outlined.

Rohit B. Sharma, Christine O. Darko, Ying Wang et al. · 1 citation

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