Author

D. Riemann

2 papers indexed here

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Open access Oct 2026

Coordinated Brain-Heart Dynamics During Human NREM Sleep

Communication between the brain and cardiovascular system is increasingly recognized as a fundamental determinant of health, yet the mechanisms coordinating neural and cardiac rhythms remain poorly understood. Sleep provides a unique physiological state for investigating neurovisceral integration because cortical slow...

C. Mikutta, Miriam Planta, Thomas Koenig et al. · bioRxiv · 0 citations

Review Sep 2026

Dose-response meta-analysis of dual orexin receptor antagonists on sleep parameters and implications for orexin-mediated arousal.

DORAs produce dose-related improvements in insomnia sleep-related outcomes, with most effects plateauing within therapeutic ranges, consistent with a pharmacodynamic ceiling whereby sufficient attenuation of orexin-mediated arousal is achieved within approved dose ranges, limiting the value of further dose escalation.

Claudio Caiazza, L. Palagini, C. Toni et al. · Sleep Medicine · 0 citations