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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

D. Root

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Open access Sep 2026

Therapy-persistent leukemia is selectively vulnerable to SLC23A1 restoration via targeting KHSRP.

Acute myeloid leukemia (AML) is prone to relapse driven by therapy-persistent residual cells. To discover specific vulnerabilities in this population, we performed genome-wide CRISPR interference screens in leukemia cells treated with multiple agents. KHSRP was the top hit, whose depletion sensitized AML cells to thera...

Qing-Yu Luo, Karley S. Whalen, Xiao-Wei Wu et al. · 0 citations
Open access Jul 2026

A comprehensive map of missense trafficking variants in rhodopsin and their response to pharmacologic correction

A high-resolution map of RHO missense variant trafficking using deep mutational scanning approaches, including a surface abundance immunoassay and a complementary membrane proximity assay, provides a valuable resource for pathogenicity assessment, genotype-phenotype correlations, and the development of targeted therape...

K. Manian, Connor H. Ludwig, Yan Zhao et al. · 0 citations

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