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Author

D. Rubinsztein

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Open access Aug 2026

G3BP1 depletion, observed in Parkinson's Disease, drives Golgi-lysosome-autophagy defects.

It is demonstrated that G3BP1 also stabilises the COPI vesicle protein beta-COP by promoting its interaction with the deubiquitinase USP10, which accelerates its proteasomal degradation.

Sarayu Ramakrishna, Laura Ryan, Sung-Min Son et al. · 0 citations
Aug 2026

Multimodal brain cell atlas across the adult macaque lifespan.

A comprehensive transcriptomic and chromatin accessibility atlas of 8 brain regions of 23 female cynomolgus macaques spanning the adult lifespan, including exceptionally old individuals establishes a foundational framework for understanding the cellular and regulatory architecture of primate brain aging and its links t...

Xiao Zhang, Guang-Shun Lai, Xiang-Yu Guo et al. · 0 citations

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