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Author

D. Rudner

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Open access Oct 2026

Efficient septum formation is essential for chromosome segregation in Bacillus subtilis when SMC function is impaired

ABSTRACT Structural maintenance of chromosomes (SMC) complexes play conserved roles in chromosome organization, segregation, and repair in all domains of life. In Bacillus subtilis, SMC is required for the segregation of newly replicated origins. To investigate whether other proteins function with SMC in this process,...

Ngoc Khanh Lai, Laura C. Lastra, Kehinde O. Adebiyi et al. · 0 citations
Open access Aug 2026

Structural basis for nutrient-activated channel opening in bacterial spore germination receptors

GerA-family germinant receptors were recently identified as ion channels that initiate germination of dormant bacterial spores in response to nutrients. Here we report 2.0-Å cryo-electron microscopy structures of apo, agonist-bound, and antagonist-bound GerA, revealing a symmetric pentamer of heterotrimers. Signaling r...

Joshua C. Cofsky, Fernando H. Ramírez-Guadiana, Briana L. Sobecks-Doherty et al. · 0 citations

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