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D. Sankoff

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Preprint Oct 2026

Tree-based Algorithms for Breakpoint Median and Near-Median Genomes

Median genomes serve as candidates for ancestral reconstruction and help study the diversity of parsimonious rearrangement solutions. However, the breakpoint median problem is NP-hard for unichromosomal genomes, and medians are non-unique, making their diversity important to study. In this paper, we develop tree-based...

Poly H. da Silva, Arash Jamshidpey, D. Sankoff · 0 citations

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