Beyond Fixed Restriction Time: Adaptive Restricted Mean Survival Time Methods in Clinical Trials
Restricted mean survival time offers a compelling nonparametric alternative to hazard ratios for right-censored time-to-event data, particularly when the proportional hazards assumption is violated. By capturing the total event-free time over a specified horizon, it provides an intuitive and clinically meaningful mea...
Jing-Hao Sun, D. Schaubel, E. T. Tchetgen Tchetgen
· Biometrika · 0 citations