Open access
Aug 2026
Inhibition of sodium-calcium exchanger by tricyclic antidepressants
Background Tricyclic antidepressants (TCAs) such as amitriptyline, desipramine, and clomipramine are widely used for the treatment of neuropathic pain, yet the cellular mechanisms underlying their analgesic effects remain incompletely understood. Increasing evidence suggests that, in addition to inhibiting monoamine re...
S. Boikov, T. V. Karelina, Maxim Nikolaev et al.
· Frontiers in Pharmacology · 0 citations