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Author

D. Sickert

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Review Open access Aug 2026

Advanced assay design for characterizing anti-drug antibody responses in clinical serum samples.

Monitoring anti-drug antibody (ADA) responses is critical for evaluating the safety and efficacy of protein therapeutics. While traditional three-tiered testing (screening, confirmation, titration) reliably identifies ADA incidence, onset and magnitude, modern, complex biologics necessitate adapting our assessment stra...

Gregor P Lotz, D. Sickert, R. Staack et al. · 0 citations

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