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Open access Jul 2026

Optimized Lipid Nanoparticles with Tail‐Modified Ionizable Lipids for Safer mRNA Delivery

ABSTRACT Despite the growing importance of lipid nanoparticles (LNPs) in mRNA therapeutics, current ionizable lipids, which comprise an ionizable head group, a linker, and hydrophobic tails that collectively govern the delivery behavior, exhibit dose‐limiting toxicity and suboptimal efficiency. Hydrophobic tail chemist...

Seo-Hyeon Bae, Jisun Lee, J. Ahn et al. · 0 citations
Open access Jan 2026

Genetic and Phylogenetic Characterization of Influenza D Viruses From South Korean Cattle, 2022–2023

Positive selection analyses revealed limited, method‐dependent signals without support from the fixed effects likelihood model, and Korean‐associated amino acid substitutions in PB1, P3, NS1, and NS2 were interpreted as lineage‐associated molecular signatures rather than evidence of adaptive evolution.

Byunghyun An, Kyungmoon Lee, Hai-Quynh Do et al. · 0 citations

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