Background Scrub typhus, an acute bacterial infection caused by Orientia tsutsugamushi, is an important, under-recognized etiology of febrile illness in South Asia. Accurate surveillance for scrub typhus in Nepal is challenging due to non-specific symptoms and limited diagnostic tools. Methods We conducted a representa...
S. Naga, S. Shahi, S. Gosai et al.· medRxiv· 0 citations
A significant and increasing burden of dengue infection in the Kathmandu Valley between 2019 and 2023 is revealed, highlighting an urgent need for immediate public health interventions to mitigate dengue's rise in Nepal's higher-altitude regions.
A. Shrestha, Melina Thapa, S. Shrestha et al.· medRxiv· 0 citations
Expanding TCV catch-up vaccination eligibility beyond 15 years up to age 35 years provides additional public health benefit in some settings, and is cost-saving in very-high-incidence settings and in drug-resistant scenarios, and cost-effective in high-incidence settings where case fatality and costs of illness are hig...
V. H. Peña-García, T. F. Menkir, C. Weyant et al.· medRxiv· 0 citations
Persistent fluoroquinolone resistance, particularly among S. Typhi and S. Paratyphi A populations in Nepal, underscores ongoing AMR challenges and highlights the need for expanded vaccine strategies targeting both pathogens.
K. E. da Silva, S. Naga, N. Katuwal et al.· medRxiv· 0 citations
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