Open access
Aug 2026
ADORA2A activation restores lysosomal function and photoreceptor outer segment degradation in stressed retinal pigment epithelium
ADORA2A activation promotes Rubicon-associated, lysosome-dependent LC3 processing of internalized POS and restores lysosomal degradative competence, supporting ADORA2A as a potential therapeutic target for early AMD.
D. Tao, Daiyi Zhou, Ming-Juan Wu et al.
· Frontiers in Physiology · 0 citations