The effect of macrophage secretome on equine endometrial fibroblast transcriptomic and functional characteristics.
Endometrial fibrosis is a main hallmark of endometrosis, a degenerative condition of the equine endometrium. Fibrosis, is characterized by the excessive accumulation of extracellular matrix (ECM) components. Current research highlights the crucial role of MΦ in activating fibroblasts in the development of fibrotic proc...