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Open access Sep 2026

687. Unraveling the suicide-inflammation axis and the moderating role of early life stress insights from polygenic risk score analyses

Abstract Background Elucidating the biological underpinnings of suicidal behavior and identifying reliable biomarkers remains a major challenge in suicide research. Equally critical is delineating the role of environmental factors, particularly early-life adversity but also acute and recent stressors in modulating suic...

X. Gonda, A. Berezvai, G. Juhász et al. · 0 citations
Open access Jul 2026

Genetic liability for morning chronotype interacts with childhood trauma to predict depressive symptoms in women.

INTRODUCTION Depression is a highly heterogeneous disorder with a similarly heterogeneous neurobiological background. Understanding separate depressive phenotypes, driven by distinct aetiological pathways like early trauma and neurobiological contributors, can improve treatment. Furthermore, sex differences must be con...

D. Gyorik, D. Torok, G. Bagdy et al. · 0 citations

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