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Review Open access Sep 2026

Immunoregenerative Microenvironment Modulation in Tendon–Ligament Regeneration: Evolution of Chitosan-Based Composite Biomaterials

Tendon and ligament injuries remain challenging to treat because healing may result in fibrosis, incomplete tendon–bone integration, impaired biomechanical properties, and reinjury. This review critically synthesizes preclinical evidence on chitosan-based composite biomaterials for tendon–ligament regeneration, focusin...

Muhammad Wibowo Ariyanto, Zairin Noor, D. Utomo et al. · 0 citations
Sep 2026

3D decellularized bovine meniscal sponge scaffold as a graft candidate: Comparative in vitro study with standard grafts.

BACKGROUND Meniscal injury disrupts knee biomechanics and accelerates degeneration. Current treatments, including allografts, are limited by donor availability and biological constraints. Decellularized extracellular matrix (ECM) scaffolds offer a promising alternative. This study evaluated a three-dimensional (3D) dec...

J. Sedar, D. Utomo, P. Widiyanti et al. · 0 citations

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