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Author

D. V. D. van den Hove

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Open access Oct 2026

Src kinase as a molecular contributor to tau pathology in Alzheimer’s disease

Tau pathology is a defining feature of Alzheimer’s disease (AD), yet the molecular factors that modulate its onset and progression remain incompletely understood. The proto-oncogene Src kinase, a non-receptor tyrosine kinase with broad roles in neuronal signaling, has been implicated in neurodegenerative processes, b...

Diego Mastroeni, Chun-Kit Chan, Nader Morshed et al. · 0 citations
Review Open access Aug 2026

When myelin breaks, tau aggregates — a new perspective on Alzheimer's disease

A myelin‐centered framework for tau pathology based on three mechanisms suggests that myelin loss may contribute to tau accumulation, clearance deficits, and spread, providing a framework for future experimental testing.

A. Tiane, D. V. D. van den Hove, T. Vanmierlo · 0 citations

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