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Author

D. Vergara

2 papers indexed here

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Open access Jul 2026

Oleoylethanolamide attenuates early skeletal muscle metabolic remodeling induced by short-term high-fat diet exposure.

Obesity develops through progressive metabolic alterations that arise long before overt disease, highlighting the need for pharmacological strategies capable of targeting the earliest tissue adaptations to fat nutrient excess. Skeletal muscle plays a central role in systemic metabolic homeostasis and is among the first...

M. Friuli, B. Eramo, Nisha Zahid et al. · 0 citations
Open access Aug 2026

Persistent lipotoxicity overwhelms adaptive capacity in human hepatic cell line.

Sustained PA/OA exposure induces a staged hepatocellular response, early lipid-buffering adaptation, intermediate metabolic compensation, and late decompensation, indicating that chronic lipotoxicity reflects progressive loss of regulatory coordination despite persistent metabolic adaptation.

I. Serra, Elisa Bisconti, Francesco Vari et al. · 0 citations

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