In recent years, extensive research has focused on fluoroquinolone–triazole hybrids, with particular emphasis on structural modifications of ciprofloxacin. In the present study, novel derivatives of lomefloxacin with a 1,4-disubstituted-1,2,3-triazole moiety were designed, synthesised, and biologically evaluated at the...
Justyna Nowakowska, Zuzanna Rzepka, A. Bąk et al.· Biomolecules· 0 citations
Melanoma is a malignant tumor that originates in pigment-producing cells called melanocytes. This type of cancer remains a major public health challenge due to its high metastatic potential and resistance to treatment. Autophagy is a catabolic process that enables the controlled degradation of damaged cellular organell...
Dominika Stencel, D. Wrześniok· International Journal of Mol...· 0 citations
Breast cancer remains one of the leading causes of cancer-related mortality in women worldwide, with estrogen receptor α (ERα) signaling playing a key role in hormone-dependent tumors. Here, we investigated the molecular basis of the anticancer activity of EB171, an amide derivative of betulonic acid, in breast cancer...
Zuzanna Rzepka, Dominika Stencel, E. Bębenek et al.· Toxicology and Applied Pharm...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
