The phenotypic distinction between MYH7 and MYBPC3, the two major causative genes of hypertrophic cardiomyopathy (HCM), remains unclear, limiting genotype-informed management. In addition, the clinical interpretation of variants of uncertain significance (VUS) poses a persistent challenge.
This study aims...
D. Zhou, M. Lu· European Heart Journal· 0 citations
Cardiac resynchronization therapy (CRT) remains limited by significant non-response rates, particularly in patients with advanced ventricular remodeling. While myocardial scar assessment provides important prognostic information, biomarkers that specifically capture the residual capacity for reverse remodeling ar...
D. Zhou, M. Lu· European Heart Journal· 0 citations
Background The clinical utility of quantitative T1 mapping in cardiac MRI is constrained by variability across acquisition protocols, and a comprehensive comparison between commonly used sequences remains unavailable. Purpose To provide a full range of cardiac MRI native T1 and extracellular volume fraction (ECV) value...
Hua-Ying Zhang, C. Cui, Wen-Li Zhou et al.· Radiology· 0 citations
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