Syntaxin 1 A knockdown suppresses hepatocellular carcinoma cell viability and invasion but induces apoptosis primarily through the AKT pathway.
OBJECTIVE Syntaxin 1 A (STX1A) was recently shown to regulate the progression of several cancers. However, the role of STX1A in hepatocellular carcinoma (HCC) remains unclear. We examined how STX1A affects HCC cell behavior and its relationship to the AKT and ERK pathways. METHODS The clinical implications of STX1A i...