Author

Da-Lu Xie

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Open access Aug 2026

Achieving Hierarchical Selective Ablation and Remodeling “Cold” Tumors via a Dual‐Organelle‐Targeted AIE Nanoplatform: Synergizing Ferroptosis, ICD, and cGAS–STING Activation

Immunotherapy has created new opportunities for treating triple‐negative breast cancer (TNBC), but its benefit is often limited by an immunosuppressive tumor microenvironment. Here, we report BMFL, a folate receptor‐targeted liposomal nanoplatform that co‐delivers a near‐infrared aggregation‐induced emission luminogens...

Wen-Kai Zhang, Xue-Ke Yan, Xiepeng Deng et al. · Aggregate · 0 citations

Sep 2026

Two-photon photodynamic induction of PANoptosis and immunogenic cell death for precision tumor eradication using a dual-organelle-targeted STING agonist.

Triple-negative breast cancer (TNBC) remains a formidable clinical challenge owing to its aggressive metastatic behavior and the absence of well-defined therapeutic molecular targets. Although photodynamic therapy (PDT) holds immense promise, its efficacy is often limited by the aggregation-caused quenching (ACQ) of co...

Hao Ren, Da-Lu Xie, Wen-Zhao Shang et al. · Acta Biomaterialia · 0 citations