Review
Open access
Aug 2026
Beyond Expression: Molecular Imaging of Claudin18.2 to Decipher Target Accessibility and Guide Precision Oncology.
Claudin18.2 (CLDN18.2) has emerged as a clinically important therapeutic target in gastrointestinal malignancies following the success of zolbetuximab-based therapy. However, unlike conventional overexpression-driven biomarkers, the clinical relevance of CLDN18.2 is fundamentally shaped by target accessibility rather t...
Yueling Deng, Jinquan Han, Xiao Zhang et al.
· Pharmacological Research · 0 citations