Polypropylene microplastics orchestrate oxidative stress microenvironment and trigger metabolic reprogramming in mouse kidney as revealed by Raman spectra and metabolomics.
The high metabolism and homeostatic roles of kidney make it susceptible to microplastics (MPs); however, the specific antioxidant targets and resulting metabolic alterations remain largely unknown. In this study, the effects of polypropylene-MPs on oxidative homeostasis were refined by discriminating protein families a...