Dai-Xuan Cui

ATF5 promotes redox homeostasis and cancer progression through nuclear-mitochondrial collaboration in pancreatic cancer

Mitochondrial dysfunction has a dual impact on the progression of pancreatic cancer (PC). While moderate impairment of mitochondrial function supports tumor growth and adaptation, severe mitochondrial damage accompanied by excessive reactive oxygen species accumulation induces mitochondria-mediated apoptosis, posin...