Extracellular vesicles from human adipose-derived mesenchymal stem cells reprogram macrophage lipid metabolism via the ABCF1/CPT1A/IL-10 axis to mitigate sepsis-induced acute lung injury
Sepsis-induced acute lung injury (ALI) is a life-threatening syndrome characterized by overwhelming inflammation, immune dysregulation, and tissue damage. Metabolic reprogramming of macrophages has emerged as a central regulator of inflammatory responses. Extracellular vesicles (EVs) derived from mesenchymal stem cel...