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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Dajiang Qin

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Aug 2026

Integrin β6-Targeted CAR-T Cells exhibit potent antitumor activity in β6-Positive pancreatic ductal adenocarcinoma and lung adenocarcinoma.

Pancreatic ductal adenocarcinoma (PDAC) and lung adenocarcinoma (LUAD) remain lethal malignancies with limited therapeutic options, highlighting an urgent need for more effective treatments. Integrin αvβ6 (ITGB6) is a receptor preferentially expressed in specific types of tumors, such as PDAC and LUAD, and represents a...

Ling-Chao Shi, L. Qin, Shu-Xin Sun et al. · 0 citations
Aug 2026

Multimodal brain cell atlas across the adult macaque lifespan.

A comprehensive transcriptomic and chromatin accessibility atlas of 8 brain regions of 23 female cynomolgus macaques spanning the adult lifespan, including exceptionally old individuals establishes a foundational framework for understanding the cellular and regulatory architecture of primate brain aging and its links t...

Xiao Zhang, Guang-Shun Lai, Xiang-Yu Guo et al. · 0 citations
Aug 2026

A single-nucleus chromatin accessibility atlas reveals epigenetic dynamics in aging mouse skeletal muscle.

The epigenetic mechanisms underlying the transition of healthy type IIb myonuclei into Ampd3+ myonuclei, revealing key chromatin remodeling events that drive this phenotypic shift are delineated, helps understand the epigenetic events underlying mammalian skeletal muscle aging.

J. An, Guang-Shun Lai, Jing Zuo et al. · 0 citations

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