Author

Dale I. Godfrey

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Open access Sep 2026

Butyrophilin 3A1 engages the CDR2δ loop of the Vγ9Vδ2+ T cell receptor.

It is shown that intracellular pAg accumulation can modulate binding of Vγ9Vδ2+ TCR in a BTN3A1-dependent manner, indicating the important role of TCR binding to BTN3A1 in pAg recognition.

Thomas S. Fulford, Marc Rigau, Jasmine Z. Yang et al. · Cell Reports · 0 citations

Open access Sep 2026

γδ T cells modulate anti-tumor immunity in small cell lung cancer.

It is demonstrated that γδ T cells are effective at tarlatamab (delta-like ligand 3 [DLL3]-CD3 bispecific T cell engager [BiTE])-redirected SCLC killing and that zoledronate can sensitize SCLC cells to γδ T cell-mediated killing.

Jin Ng, Yue You, Tina Zhang et al. · Cancer Cell · 0 citations