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Author

Dalia H. El-Kashef

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2 papers indexed here

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Oct 2026

Saxagliptin Attenuates Thioacetamide-Induced Liver Fibrosis in Rats in Association with Changes in SIRT1/Nrf2/HO-1 Signaling, Oxidative Stress, and Apoptosis.

PURPOSE Currently, no universally effective treatment exists to stop or reverse the development of liver fibrosis. Saxagliptin (SAX), a dipeptidyl peptidase-4 (DPP-4) inhibitor, has demonstrated extra-glycemic benefits, including anti-inflammatory and anti-apoptotic properties, but its role in hepatic fibrogenesis has...

M. Alsugoor, N. Alsuhaymi, S. El Awdan et al. · 0 citations
Open access Oct 2026

Saroglitazar protects against cadmium-induced hepatorenal injury in rats by suppressing NF-κB and upregulating Nrf2

Introduction Cadmium (Cd) toxicity is one of the major public health problems because of its long half-life (10–30 years). Exposure to Cd can cause toxicity that affects several organs, including the liver and the kidney. Saroglitazar is highlighted in this study as a potential preventative medication against hepatic-r...

A. Alanazi, Hoda E. Kafl, Dalia H. El-Kashef et al. · 0 citations

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