Author

Dalia K. Zaafar

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Review Oct 2026

From CYP450 pharmacogenomics to personalized medicine: clinical evidence, dosing guidelines, and future perspectives.

Interindividual variability in drug response remains a critical challenge in contemporary pharmacotherapy, and cytochrome P450 (CYP450) genetic polymorphisms are a principal determinant of this heterogeneity. The CYP450 superfamily mediates the oxidative biotransformation of 70-80% of clinically prescribed medications....

K. Aldossary, Dalia K. Zaafar, Nada A. Alsaleh et al. · Pharmacogenomics (London) · 0 citations

Review Oct 2026

Novel Anti-Obesity Drugs: Pharmacokinetics, Pharmacodynamics, and Precision Dosing

A. M. Badawoud, Dalia K. Zaafar, H. Alrasheed et al. · Current Pharmacology Reports · 0 citations

Open access Aug 2026

Ivabradine alleviates the cisplatin-induced cardiotoxicity in rats through regulating the crosstalk between MLCP/PKG, MEK/ERK pathways and miRNA-34a levels

IVA significantly attenuates Cis-induced cardiotoxicity through antioxidant, anti-inflammatory, anti-apoptotic, and miRNA-34a-mediated mechanisms involving multiple cardioprotective signaling pathways.

N. Aldabaan, Basel A. Abdel-Wahab, Ehab A. M. El-Shoura et al. · Immunopharmacology and immun... · 0 citations