Open access
Sep 2026
HOTAIR Promotes Prostate Cancer Progression by facilitating CDK9-Pol II Association and Transcriptional Elongation
Previous research has predominantly focused on the regulatory role of lncRNA HOTAIR in gene silencing by interacting with the Polycomb repressive complex 2 (PRC2), but its direct role as a transcriptional activator remains less well characterized. Here, our study reveals a novel regulatory mechanism of HOTAIR, which fa...
Yu-Yang Qian, Bo Wang, Guang-Song Su et al.
· International Journal on Bio... · 0 citations