Open access
Oct 2026
Curcumin alleviates metabolic dysfunction-associated steatotic liver disease via gut microbiota-dependent epigenetic alterations
A novel gut-liver axis is revealed in MASLD pathogenesis, demonstrating that Cur alleviates hepatic steatosis by targeting the microbiota-KYN-AHR-H3K27ac-Cebpb epigenetic axis, positioning Cur supplementation and KYN modulation as promising therapeutic strategies for MASLD intervention.
Yong Zhu, Jin-Hu Ma, Dan-Hong Wang et al.
· Molecular Biomedicine · 0 citations