Articular cartilage has limited intrinsic repair capacity, and current clinical approaches often fail to restore durable hyaline cartilage. Three-dimensional bioprinting offers spatial control over cells, biomaterials, and bioactive cues, creating opportunities to fabricate patient-specific constructs that recapitulate...
He-Bin Ma, Zhen Yang, Ya-Jing Li et al.· International Journal of Bio...· 0 citations
Osteoarthritis (OA) is a whole-joint disease characterized by progressive structural degeneration and chronic low-grade inflammation affecting the cartilage, synovium, subchondral bone, and immune compartments. It is a complex degenerative disorder associated with substantial morbidity, heterogeneous clinical trajector...
Zhen Yang, Qi-Yuan Lin, Hao Li et al.· Bioactive Materials· 0 citations
Bone defects remain a significant clinical challenge due to the limited regenerative capacity. Biomaterials can offer effective therapeutic approaches to address this challenge, where their physical properties play a critical role in determining the success of regeneration. Here, we fabricated cryogelated 3D porous sca...
Qianqian Chen, Shichun Xu, Yiqi Su et al.· Stem cell research & therape...· 0 citations
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