Acute ischemic stroke initiates a rapid convergence of excitotoxicity, calcium overload, oxidative stress, neuroinflammation, and energetic failure. Although reperfusion therapies remain central to acute care, they do not directly address the structural failure of injured neuronal networks. This narrative review examin...
David Bar-Or, Gregory Thomas, Alexa Schroder et al.· Frontiers in Neuroscience· 0 citations
A complementary conceptual framework in which aging is viewed as progressive impairment of biological self-correction: the distributed capacity to sense consequential perturbations, scale an appropriate response, scale an appropriate response, repair or remove damage, terminate the response, and recover or adaptively r...
David Bar-Or, Jason S. Williams, Daniel A. Paredes· Geriatrics· 0 citations
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