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Daniel A. Skelly

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Open access Sep 2026

CellMAGE: cell-type deconvolution for multi-parent population analysis of gene expression

Single-cell RNA-sequencing remains prohibitively expensive for multiparental population (MPP) studies. Existing deconvolution methods treat bulk RNA-seq as genetically anonymous mixtures, but in MPPs, the proportional contribution of each parental strain to each progeny’s transcriptome is already known. CellMAGE (Cell-...

Robyn L. Ball, Alyssa Klein, Ashley A. Auth et al. · 0 citations

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