Daniel E. Voth

Breathing and burning: metabolic control of alveolar macrophages by intracellular bacterial pathogens

Alveolar macrophages (AMs) are the lung’s phagocytic immune sentinels, programmed to maintain homeostasis while defending against inhaled pathogens. AM metabolism is shaped by both developmental origin and the alveolar microenvironment. Embryonically-derived AMs populate the lungs early in life and develop into long-li...