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Daniel Guo

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Review Open access 2026

The CRISPR Era and Beyond: Technical Milestones and Future Directions in Sickle Cell Disease Therapeutics

Sickle cell disease (SCD) is a major hereditary blood disorder affecting approximately 8 million people worldwide, historically managed through symptomatic care and small-molecule disease-modifying agents. The pivotal 2023 FDA approvals of lovotibeglogene autotemcel (Lyfgenia) and exagamglogene autotemcel (Casgevy) mar...

Daniel Guo · 0 citations

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