Open access
Sep 2026
A molecular and spinal circuit basis for the functional segregation of itch and pain
Summary The dorsal horn is remarkably diverse, yet how this cellular complexity enables discrimination of sensory modalities remains a fundamental question. Neurons expressing gastrin-releasing peptide receptor (Grpr+) have long been considered dedicated to itch, yet broad activation also evokes pain-related behavior....
M. Noh, Kelly A. Corrigan, Sean-Paul G. Williams et al.
· Neuron · 0 citations