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Daniel P. Becker

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Open access Jul 2026

N-Heterocyclic sulfonamides and sultams as inhibitors of the bacterial enzyme diaminopimelate desuccinylase (DapE).

The synthesis of N-heterocyclic sulfonamides and N-aryl sultams is described to explore the effects of heterocycles and conformational constraints on DapE inhibition to explore the effects of heterocycles and conformational constraints on DapE inhibition.

Sebastian Flieger, Emma H. Kelley, Megan Beulke et al. · 0 citations

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