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Author

Daniel Scherr

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Open access Sep 2026

Impaired Proteostasis is an Early Feature of the Diabetic Heart in Humans and Mice

Diabetes and obesity increase cardiac lipid levels leading to cardiomyopathy and heart failure. We hypothesized that intermittent fasting would reduce cardiac lipid levels. Surprisingly, intermittent fasting increased myocardial triglyceride content, but rescued mortality and attenuated cardiomyopathy in mice overexpre...

David R. Rawnsley, Chen Zhao, Xiu-Cui Ma et al. · 0 citations

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