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Daniel Severin

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Open access Aug 2026

Visual deprivation in adulthood engages presynaptic plasticity of thalamocortical synapses

It is shown that robust and reversible plasticity can be induced in adult mice by prolonged dark exposure (DE) and light reintroduction (LRx) and that robust plasticity is engaged at thalamocortical synapses in adults by visual deprivation, a non-invasive manipulation with therapeutic potential.

S. Murase, Daniel Severin, Andrew Pranger et al. · bioRxiv · 0 citations