Author

Daniel T. Utzschneider

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Open access Sep 2026

In vivo effect of anti-PD-1 on HIV-specific CD8+T-cells in men with HIV

It is shown that a single dose of anti-PD1 increases HIV-specific CD8 + T cells in some but not all participants, and an inverse relationship between an increase in cell associated viral RNA following anti-PD1 and the percentage of specific T-cell clusters prior to administration of anti-PD-1 is demonstrated.

Céline Gubser, Lakshmi Rajdev, Chris Y. Chiu et al. · Nature Communications · 0 citations

Review Open access Jul 2026

Targeting the fate of exhausted CD8+ T cells.

This emerging view frames exhaustion as a context-dependent extension of the memory program rather than its collapse, and highlights how these insights can inform new approaches to manipulate T cell fate for therapeutic benefit.

Daniel T. Utzschneider, Stephen J. Turner · Trends in immunology · 0 citations