Open access
Aug 2026
Proteoform-Resolved Cross-Linking Reveals Environment-Dependent Structural Effects of α-Synuclein S129 Phosphorylation.
A proteoform-by-environment model for IDP structure is established, in which phosphorylation effects are not fixed but are rewritten by the surrounding chemical environment, which distinguishes broad contact accessibility from the residue-level contacts that dominate each condition.
Ashlyn N. Dollar, Daniel W. Kelley, Ian K. Webb
· Journal of the American Chem... · 0 citations