Electron paramagnetic resonance (EPR) spectroscopy has evolved into a powerful tool for studying matter containing unpaired electrons. By probing electron spin interactions with their environment and with other spins, EPR provides insight into electronic structure, local chemical environments, molecular motion, and int...
Daniella Goldfarb, Gunnar Jeschke, E. J. L. McInnes et al.· Science Advances· 1 citation
These studies establish EPR spectroscopy as a valuable biophysical tool for resolving conformational ensembles and structural heterogeneity underlying Hsp90’s function, with general relevance to the structural biology, spectroscopy, and chaperone fields, and pave the way for future in vitro and in-cell investigations o...