Aging is the primary risk factor for neurodegenerative disease, yet the protein signatures that distinguish physiological brain aging from pathological decline remain incompletely defined in translational models. Using the targeted NULISAseq proteomic platform, we profiled cerebrospinal fluid (CSF) and plasma from 66 r...
Giovanne B. Diniz, Kayla Schwartz, Carissa T. Erices et al.· GeroScience· 0 citations
Post-COVID-19 syndrome (PCS) is an escalating global health concern, marked by persistent cognitive, neurological, and psychiatric symptoms following acute SARS-CoV-2 infection. Although its underlying mechanisms remain incompletely understood, mounting evidence implicates chronic neuroinflammation as a key driver. Sus...
Daniel Martins, Danielle Beckman, M. Loggia et al.· Translational Psychiatry· 2 citations
This work uses an adeno-associated virus-induced longitudinal macaque model of Alzheimer’s disease to examine early changes in behavior, neuronal population activity, and pathology and suggests that early disease is accompanied by a progressive loss of coordinated population activity.
Douglas A. Ruff, Drew E. G. Sheets, Ramanujan Srinath et al.· Proceedings of the National...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.